Importance Informed consent is essential to ethical, rigorous research and is important to recruitment and retention in cancer trials.Objective To examine cancer clinical trial (CCT) participants’ perceptions of informed consent processes and variations in perceptions by cancer type.Design and Setting and Participants Cross-sectional survey from mixed-methods study at National Cancer Institute–designated Northeast comprehensive cancer center. Open-ended and forced-choice items addressed: (1) enrollment and informed consent experiences and (2) decision-making processes, including risk-benefit assessment. Eligibility: CCT participant with gastro-intestinal or genitourinary, hematologic-lymphatic (...) malignancies, lung cancer, and breast or gynecological cancer (N = 334).Main Outcome Measures Percentages satisfied with consent process and information provided; and assessing participation’s perceptions of risks/benefits. Multivariable logistic or ordinal regression examined differences by cancer type.Results Most patient-participants felt well informed by the consent process (more than 90% overall and by cancer type) and. most (87.4%) reported that the consent form provided all the information they wanted, although nearly half (44.8%) reported that they read the form somewhat carefully or less. More than half (57.9%) said that talking to research staff (i.e., the consent process) had a greater impact on participation decisions than reading the consent form (2.1%). A third (31.1%) were very sure of joining in research studies before the informed consent process (almost half of lung cancer patients did—47.1%). Most patients personally assessed the risks and benefits before consenting. However, trust in physicians played an important role in the decision to enroll in CCT.Conclusions and Relevance Cancer patients rely less on written features of the informed consent process than on information obtained from the research staff and their own physicians. Research should focus on information and communication strategies that support informed consent from referring physicians, researchers, and others to improve patient risk-benefit assessment and decision-making. (shrink)

La autora presenta una critica a la concepcion clasica de los sentidos asumida por la mayoria de autores naturalistas que pretenden explicar el contenido mental. Esta crítica se basa en datos neurobiologicos sobre los sentidos que apuntan a que estos no parecen describir caracteristicas objetivas del mundo, sino que actuan de forma ʼnarcisita', es decir, representan informacion en funcion de los intereses concretos del organismo.El articulo se encuentra también en: Bechtel, et al., Philosophy and the Neuroscience.

The primary aim of this study is to dissolve the mind-body problem. It shows how the ‘problem’ separates into two distinct sets of issues, concerning ontology on the one hand, and explanation on the other, and argues that explanation – whether or not human behaviour can be explained in physical terms – is the more crucial. The author contends that a functionalist methodology in psychology and neurophysiology will prove adequate to explain human behaviour. Defence of this thesis requires: an examination (...) of the mental/physical dichotomy, and its rejection in favour of a distinction between psychological and physical terms; a description and discussion of functionalism in psychology and neurophysiology, showing how the notorious problem of the necessary intensionality of psychological terms may be circumvented; an examination of the role of computer simulation in psycho-physical research; and an explanation of how the phenomena of sentience fit the functional framework. The book concludes that the thesis presented is in all essentials that of Aristotle; Aristotle had no ‘mind-body problem’, and were it not for a subsequent over-obsession with Cartesian scepticism, we need not have had one either. (shrink)

A common view in both philosophy and the vision sciences is that, in human vision, wavelength information is primarily ‘for’ colouring: for seeing surfaces and various media as having colours. In this article we examine this assumption of ‘colour-for-colouring’. To motivate the need for an alternative theory, we begin with three major puzzles from neurophysiology, puzzles that are not explained by the standard theory. We then ask about the role of wavelength information in vision writ large. How might wavelength information (...) be used by any monochromat or dichromat and, finally, by a trichromatic primate with object vision? We suggest that there is no single ‘advantage’ to trichromaticity but a multiplicity, only one of which is the ability to see surfaces and so on as having categorical colours. Instead, the human trichromatic retina exemplifies a scheme for a general encoding of wavelength information given the constraints imposed by high spatial resolution object vision. Chromatic vision, like its partner, luminance vision, is primarily for seeing. Viewed this way, the ‘puzzles’ presented at the outset make perfect sense. 1 Reframing the Problem1.1 Introduction1.2 Three puzzles1.2.1 Why is trichromatic vision an anomaly in diurnal mammals?1.2.2 Why does the colour system occupy such a large and central part in human vision?1.2.3 Why are the blue cones so rare?1.3 Recasting the question2 The Costs and Benefits of Spectral Vision2.1 Spectral information and object vision2.2 Encoding the spectral dimension of light2.2.1 ‘General’ versus ‘specific’ encoding2.2.2 Spectral encoding and the monochromat2.2.3 Spectral encoding and the dichromat2.2.4 Spectral encoding and the human trichromat2.3 Three puzzles revisited2.3.1 Why is trichromatic vision an anomaly in diurnal mammals?2.3.2 Why does the colour system occupy such a large and central part in human vision?2.3.3 Why are the blue cones so rare3 Conclusion. (shrink)

This paper explores the relationship between common-sense psychology (CSP) and scientific psychology (SP) — which we could call the mind-mind problem. CSP has come under much attack recently, most of which is thought to be unjust or misguided. This paper's first section examines the many differences between the aims, interests, explananda, explanantia, methodology, conceptual frameworks, and relationships to the neurosciences, that divide CSP and SP. Each of the two is valid within its own territory, and there is no competition between (...) them — primarily because CSP is not, and has no interest in being, a scientific theory. In the second section some implications are drawn. First, neither CSP nor SP has the mind-body problem in its familiar form. Second, CSP, for excellent reasons, is not equipped to handle irrational or non-rational behaviour; there are some grounds for believing that this can and should be the task of SP. Third, philosophical psychology, or armchair theories of action, perception, etc., are doomed to failure. And, fourth, the realm of the psychological is so heterogeneous that no single model for either CSP or SP is likely to succeed. (shrink)

It is notorious that Aristotle gives two distinct and seemingly irreconcilable versions of man's eudaimonia in the Nicomachean Ethics. These offer conflicting accounts not only of what the good man should do, but also of what it is good for a man to do. This paper discusses the incompatibility of these two pictures of eudaimonia, and explores the extent to which the notions of 'the life of a good man' and 'the life good for a man' can be successfully united (...) in a single concept of eudaimonia. (shrink)

In Consciousness Explained, Daniel Dennett presents the Multiple Drafts Theory of consciousness, a very brief, largely empirical theory of brain function. From these premises, he draws a number of quite radical conclusions—for example, the conclusion that conscious events have no determinate time of occurrence. The problem, as many readers have pointed out, is that there is little discernible route from the empirical premises to the philosophical conclusions. In this article, I try to reconstruct Dennett's argument, providing both the philosophical views (...) behind the empirical premises, and the hidden empirical arguments behind the derivation of the philosophical conclusions. (shrink)

Throughout the text, fundamental questions concerning the nature of visual perception are addressed.

This article finds little to disagree with in Neurophilosophy The sole area of disagreement is with Professor Churchland's attitude to common?sense psychology. Unfortunately, though, the author has already attempted to describe what should be the proper view of common?sense psychology in an earlier article in this very journal. Therefore the present article tries to build on the earlier one, advocating an instrumentalist constraal of many ordinary?language mental terms ? a construal with which Professor Churchland is unlikely to agree, but which, (...) if she did agree, would give her further ammunition with which to beat her opponents. The other main strand of this article suggests that Aristotle has anticipated Professor Churchland (and also most other theoreticians of psychology and physiology), and so, willy?nilly, we are ? correctly ? returning to an Aristotelian picture of human capacity and activity. (shrink)

Some authors argue that the ethics of medical care and the ethics of research differ, and that it is a mistake to conflate the two. They propose “that medical research and medical treatment are two distinct forms of activities, governed by different ethical principles.” This raises the question of whether physicians who are also clinical investigators may separate their role as physician from that of researcher when they are involved in clinical trials, thereby avoiding the obligations required in the physician-patient (...) relationship. Miller and Brody suggest that medical training is to blame for what they believe is the physicians’ tendency to confound the obligations of research and practice. “Physician-investigators, after all, went to medical school” they explain. They believe that considering research with patients outside the ethical framework of the physician-patient relationship may be “difficult and threatening” to physicians who have “psychological needs” to consider the ethical obligations flowing from their relationship with their patients. (shrink)

This chapter looks at the impact of recent societal approaches of knowledge and science from the perspectives of two rather distant educational domains, mathematics and music. Science’s attempt at ‘self-understanding’ has led to a set of control mechanisms, either generating ‘closure’—the scientists’ non-involvement in society—or ‘economisation’, producing patents and other lucrative benefits. While scientometrics became the tool and the rule for measuring the economic impact of science, counter movements, like the slow science movement, citizen science, empowering music-art initiatives and other (...) critical approaches focus on intrinsic and ethical questions of education and knowledge. Thinking about knowledge and research in terms of quantifiable products impacts heavily upon the domains of science and arts, while the complexity of knowledge acquisition forces society to consider also other parameters like equality, personal development and participatory processes. (shrink)

In Being and Nothingness Jean-Paul Sartre contends that the self's fundamental relation with the other is one of inescapable conflict. I argue that the research of the last few decades on the ability of infants - even newborns - to imitate the facial expressions and gestures of adults provides counter-evidence to Sartre's claim. Sartre is not wrong that the look of the other may be a source of self-alienation, but that is not how it functions in the first instance. An (...) earlier and more primary form of looking with and at the other is a source of self-discovery. In early imitation, the infant and adult each see the other not as objects of experience but as subjects of action. Such looking is necessary for the infant to realize its own potential as a self-conscious, goal-directed subject of perception and action. (shrink)

A traditional association of judgment with "reason" has drawn upon and reinforced an opposition between reason and emotion. This, in turn, has led to a restricted view of the nature of moral judgment and of the subject as moral agent. The alternative, I suggest, is to abandon the traditional categories and to develop a new theory of judgment. I argue that the theory of judgment developed by Justus Buchler constitutes a robust alternative which does not prejudice the case against emotion. (...) Drawing on this theory I then develop how to conceptualize the ways in which feeling and emotion can be (or be components of) moral judgments. (shrink)

The burden of this article is that although the idea of `the self'which Galen Strawson decribes in his target article is initially very attractive, it eventually doesn't work. There is a lot of competition for a `pole position'notion -- `human', `person', psuche, `soul', even `sake'-- and the idea of `self'does not seem to deserve the prize. What Strawson wants to do with the notion of a `self'can be done equally well, and more economically, by the first-person pronoun. A question raised (...) repeatedly is: `What is a self worth wanting?'Perhaps the greatest area of disagreement with Strawson's article is with his idea that `the self'needs to have little or nothing to do with time-related plans and emotions: guilt and remorse; pride; hope and expectation; career choices . . . even such apparently mundane things as pension-plans -- in fact, any long-term forward- or backward-looking psychological phenomena. The question of realism is pressed. (shrink)

This article reviews four areas of pediatric research in which we have identified questionable levels of allowable risk, exceeding those foreseen by the Commission. They are the following: the categorization of increasingly risky interventions as minimal risk in a variety of protocols; the increasing number of applications for federal panel review of research not otherwise approvable because of higher projected risk levels; research on asymptomatic at risk children; and the inclusion of children and adolescents in placebo-controlled trials for participants of (...) all ages without performing subgroup analysis. While embracing the imperative to include children in research is an encouraging step towards providing the pediatric population with effective medical care and finally eradicating the therapeutic orphan, we must ensure that this research does not become overly permissive. (shrink)

Porter and Kramer are very clear that shared value is not corporate social responsibility. Not only do they criticize the four principles on which CSR rests: moral obligation, sustainability, license to operate, and reputation, as ineffective and vague, they maintain that the only reason for companies to engage in sustainability projects is to decrease costs and thus increase profits, not because they have a corporate responsibility to help protect the environment the people who dwell in it. Because social problems cause (...) extra costs for companies and thus decrease profits, they say that companies should have strategies that might appear to be socially responsible, but are not because the intent is to improve profits. This paper will describe the current definitions and focus of CSR, explain shared value, and then propose ways that commitment to CSR can be made public by leaders and their businesses, such as using social license to operate, third-party assessors, and new business structures. (shrink)

In assembling scholars for the John Dewey Symposium for the 2015 Annual Meeting in Chicago, I sought thinkers who would critically engage Maxine Greene’s philosophy of democratic education. The recent death of Greene, long-time member of the Society, friend and teacher of many members, and John Dewey Lecturer in 1988, had left a powerful absence among educational philosophers, and many had honored her legacy with loving tributes. The Symposium’s aim was to bring together scholars in critical engagement with her work.Greene (...) had interpreted, critiqued, and in some ways enlarged Deweyan philosophy for much of her career. Key to her democratic educational thought was the concept of the social imagination:We... (shrink)

Nativists about syntactic processing have argued that linguisticprocessing, understood as the implementation of a rule-basedcomputational architecture, is spared in Williams syndrome, (WMS)subjects – and hence that it provides evidence for a geneticallyspecified language module. This argument is bolstered by treatingSpecific Language Impairments (SLI) and WMS as a developmental doubledissociation which identifies a syntax module. Neuroconstructivists haveargued that the cognitive deficits of a developmental disorder cannot beadequately distinguished using the standard gross behavioural tests ofneuropsychology and that the linguistic abilities of the (...) WMS subject canbe equally well explained by a constructivist strategy of neurallearning in the individual, with linguisitic functions implemented in anassociationist architecture. The neuroconstructivist interpretation ofWMS undermines the hypothesis of a double dissociation between SLI andWMS, leaving unresolved the question of nativism about syntax. Theapparent linguistic virtuosity of WMS subjects is an artefact ofenhanced phonological processing, a fact which is easier to demonstratevia the associationist computational model embraced byneuroconstructivism. (shrink)

The book details several well-argued theories aiming to explain how the full, cohesive vista of human vision and perception is possible. The main query is broken down into several parts. The first deals with how we organize our representations of the world and whether these are processed and connected in a logical and sentential manner, or if these involve random connections across our neurons. The next part focuses on the amount of detail in the visual representations themselves and yields two (...) opposing theories: the “Literalist View”—“You See What You Think You See”—and the non-Literalist or “Functional View”—“You Don't See What You Think You See.” Also discussed is whether the intentional content of neural representations is individuated by factors external or internal to the subject. The last part of the chapter tackles how visual perception is processed and unified via the “Feature Integration Theory” or the “Recollective Theory.”. (shrink)

The chapter summarizes the discussions on perception between Churchland, Ramachandran, and Dennett. The arguments focus on a central issue—the relationship between the actual visual experience and one's internal neural representations. A detailed discourse on Dennett's Theory of Consciousness is provided, with particular focus on his explanations on the phenomenon of “filling in.” The chapter points out several weaknesses in Dennett's work, arising from his attempt to reconcile essentially divergent beliefs on philosophy as it relates to persons and science as it (...) relates to “sub-personal” processing. Three concerns are identified: first, the supposed transparency of content and a person's capacity to make mistakes in describing one's own visual experience must be reconciled; second, an explanation on the similarity of our neurological experiences with both abstract and detailed veridical content must be given; and third, computational content must be provided to support his claim of content being transparent to consciousness. (shrink)

Experimental encounters in music and beyond opens a necessary dialogue on experimental practices in the arts and negotiates their place in contemporary society. Going beyond the music-historical usage of the term "experimental", this book reimagines experimentation as an open working definition encompassing multiple forms of artistic attitudes and processes. The texts, images, and sounds offer multiple traces, faces, and spaces, revealing what experimentalism in music and the wider arts entails today. With perspectives from a range of disciplines - from choreography (...) through composition to philosophy and beyond - the different experiences and artistic projects documented and discussed explore the complexity of experimentation in a way that is all the richer for being never-ending."--Page 4 of cover. (shrink)